Disk 2 of FSX will not load

Hi

I am trying to load FSX Standard Edition onto a PC for my kids. I have no issues with the first disc, but when it asks for the second disk, it does not pick it up! It constantly comes back with "insert disk 2" but when I click OK it never starts that disk.
Now my PC sees the disc, and I can open and see the files on it, but it just refuses to load the disk.
Can anyone suggest what the issue may be here?
During instal, the only thing I am changing is the install directory to a secondary HDD (my system disk does not have enough space left on it)

Any suggestions or pointers are greatly appreciated.

Try uninstalling any DVD-ROM software like Nero or Roxio. Also, try turning off your antivirus/antisoyware software during installation.