Ok, starting from the beginning then...
First, you need the frequency of the VOR to tune into the NAV1 box.
Secondly, you need to identify it - you do this by using the VOR selector on the communication panel so you hear the morse ident. This checks you have the right beacon. Note, that this point is vital in the real world, but quite obviously, fairly unimportant in the sim.
Thirdly, you need to display the radial you want to fly, and then fly it! Simple.
Point 3 is the bit where the learning starts.
A VOR is a radio beacon (often co-located with a DME, which gives you the distance from the beacon) that has 360 radials. You can track any number of those 360 radials, by using an HSI. That's the instrument with the crossbars and the 360 degree "compass" card on the outside of the instrument with the CRS (course) selector in the bottom corner.
In your example, you want to know how to fly towards a VOR that you don't know the location of. In that example, follow steps 1 and 2. Then, turn the OBS (omni-bearing selector) until the CDI (course deviation indicator - the vertical bar on the dial) is in the centre. Then note whether the instrument, via the white flag, is telling you, that you are TO or FROM the beacon. If you want to fly towards it, turn the dial until you it says TO. Make sure you check whether you are TO or FROM though, because the CDI will centre in both senses. So, now you have the TO reading, and you have a centred CDI.
The next step is to change the heading of the aircraft to the reading that is at the top of the OBS, by banking towards it. This will displace the CDI slightly, but the way the CDI works is that you fly towards the line. So if the line deviates left, fly left. If it deviates right, fly right. Once the heading is the same as that selected by the OBS and needle centred, you are flying in a straight line, with corrections, towards the beacon.
Once you over fly it, the white flag goes to FROM and you're flying from the beacon on the same radial.
That covers the instance of flying to a VOR that you don't know the location of but doesn't really cover the VOR to VOR navigation side of things. I'd suggest you have a play around with this: http://www.luizmonteiro.com/Learning_VOR_Sim.aspx - it's a lot easier than doing it in the sim.
It's hard to get to grips with in the first instance, but stick at it and it'll come.
If you need more information, let me know.